Technological advances offer new paradigms for university training. In particular, multimedia tools have
strengthened the distance learning and e-learning approaches. E-Learning is a subset of two large worlds,
specifically, “information technology” and “education and training.” Converting a traditional course to e-learning may represent a complex endeavour, and requires accurate planning, monitoring, and control to make the conversion effective and economical. In this paper, an e-learning model and guidelines for developing countries are presented. Then, the case study of the first e-University (or VirtualUniversity) established in Iran is reported.